CuratedFit
Last reviewed:
7/16/26
Last updated:
10/6/26
Vitabiotics
Wellzyme Digestive Enzymes Advanced
15 Enzyme Formula
A broad spectrum digestive enzyme capsule with 15 distinct enzyme activities, each disclosed individually rather than folded into a single combined figure.
Gut Health Support
60 Capsules
2 to 3 capsules / main meal
CURATEDFIT SUMMARY
Passes because every one of the 15 enzyme activities is disclosed individually, with its own specific activity unit and milligram amount, rather than being grouped into an undisclosed blend. All active ingredients are biologically derived enzymes. No synthetic preservatives or artificial colors are present. The remaining gaps, independent lab verification, heavy metals testing, and confirmed manufacturing location, are transparency limitations, not failures.
WHAT IT IS
A vegan capsule providing 15 distinct digestive enzyme activities, spanning protein, carbohydrate, and fat digesting enzymes. The formula includes a relatively high dose of lactase specifically aimed at supporting lactose digestion. Vitabiotics positions this as its most advanced formula in the Wellzyme range, distinct from a simpler six enzyme version sold under the same brand.
WHO IT IS FOR
Someone who wants a broad spectrum digestive enzyme supplement with full visibility into exactly which enzymes are included and at what activity level, rather than a generic "digestive enzyme blend" with no individual breakdown.
INGREDIENT BREAKDOWN
Protease
7,500 HUT, 8 mg, per 3 capsules
Protein digestion
Amylase
3,000 DU,19 mg, per 3 capsules
Starch and carbohydrate digestion
Glucoamylase
30 AGU, 26 mg, per 3 capsules
Starch and carbohydrate digestion
Alpha-Galactosidase
30 GalU, 1 mg, per 3 capsules
Complex carbohydrate digestion
Lipase
150 FIP, 500 µg, per 3 capsules
Fat digestion
Lactase
4,500 FCC, 47 mg, per 3 capsules
Lactose digestion
Beta-Glucanase (providing Cellulase 150 CU and Beta-Glucanase 45 BGU)
Combined activity, 8 mg, per 3 capsules
Fibre digestion
Maltase
30 DP°, 4 mg, per 3 capsules
Starch and carbohydrate digestion
Xylanase
30 XU, 200 µg, per 3 capsules
Fibre digestion
Invertase
30 SU, 150 µg, per 3 capsules
Sugar digestion
Pectinase
45 Endo PGU, 5 mg. per 3 capsules
Fibre digestion
Hemicellulase
15 HCU, 30 µg, per 3 capsules
Fibre digestion
Papain
1,500 PU, 30 µg, per 3 capsules
Protein digestion
Bromelain
30 GDU, 11 mg, per 3 capsules
Protein digestion
Enzyme sourcing
Enzymes of this kind are typically produced through fungal fermentation (for enzymes like amylase, glucoamylase, and protease) or extracted directly from plant sources, with Bromelain sourced from pineapple stem and Papain sourced from papaya. This label does not state the specific source organism for each enzyme, so the general production method described here reflects standard industry practice rather than a confirmed, product specific disclosure.
Beta-Glucanase line item
The label lists Beta-Glucanase at 8 mg, then notes this single ingredient provides both Cellulase and Beta-Glucanase enzyme activity. This reflects a single enzyme preparation with two measurable activities, not an undisclosed blend of separate ingredients.
Other ingredients
Rice Dextrin (bulking agent), Hydroxypropylmethylcellulose (capsule shell), Medium Chain Triglycerides (carrier for the enzyme preparation)
CERTIFICATIONS
Informed Sport
Not Confirmed
Banned substance tested
Not Confirmed
GMP Certified
Not Confirmed
Heavy metals tested
Not Confirmed
BRCGS
Not Confirmed
FSSC 22000
Not Confirmed
CURATEDFIT STANDARD CHECK
Pass
As Natural As Possible
All 15 enzyme activities are biologically derived, no synthetic active ingredients
Info
Contains What It Claims
Each enzyme's activity unit and amount is disclosed individually. CuratedFit has not seen independent lab verification of these figures
Pass
Every Ingredient Earns Its Place
Rice Dextrin, capsule shell, and Medium Chain Triglycerides all serve clear functional roles. No preservatives or artificial colours present
Pass
No Insect-Derived Ingredients
No animal or insect derived ingredients present
Pass
No Proprietary Blends
Every enzyme is disclosed individually with its own activity unit and amount, nothing is grouped into an undisclosed blend
Pass
Allergen Declaration
Made in a site that may handle nuts, disclosed by manufacturer. Gluten free
Pass
Sugar Content Declared
No sugar ingredient present
Pass
Artificial Sweeteners and Flavorings
None present
Info
Heavy Metals and Contaminants
Not addressed on the label. No third party contaminant testing referenced
Pass
Banned Substance Risk Declared
Digestive enzymes only, no stimulant or hormonal precursor compounds
Info
Country of Manufacture Noted
Not explicitly confirmed on the pages reviewed
TRANSPARENCY NOTE
This is one of the more transparent enzyme labels reviewed for the catalogue so far. Every one of the 15 claimed enzyme activities appears on the nutritional panel with its own specific activity unit and amount, rather than a single combined figure or a generic "digestive enzyme blend" descriptor that some competing products use. The Beta-Glucanase line item, which shows one ingredient contributing two measurable activities, is a normal feature of enzyme preparations rather than an undisclosed blend.
All active ingredients here are enzymes, which are inherently biological in origin regardless of whether they come from fungal fermentation or direct plant extraction, so there is no natural origin concern of the kind seen with synthetic vitamins or industrially manufactured minerals.
The remaining Info flags reflect standard limitations for this product category. No independent lab verification of activity units is available, no heavy metals testing is referenced, and the exact manufacturing location is not stated, though Vitabiotics is a UK registered company. None of these prevent evaluating the formula itself.
FREQUENTLY ASKED QUESTIONS
Why does this label show activity units instead of just a milligram amount for each enzyme?
Enzymes work by acting on a specific target substance, called a substrate. Milligrams tell you how much material is present, but not how effective that material actually is at doing its job, since enzyme potency varies by source and preparation batch. Activity units solve that by measuring how much of the target substance a given amount of enzyme can break down under standardised lab conditions in a fixed time. Two products could list the same milligram amount of an enzyme and have very different real world potency, which is why activity units are generally treated as the more meaningful figure for enzymes.
What do HUT, DU, AGU, FIP, and the other activity units actually stand for?
Each abbreviation refers to a specific standardised test method tied to that enzyme's target substrate:
HUT (Hemoglobin Unit, Tyrosine base) measures protease activity against protein
DU (Dextrinizing Units) measures amylase activity against starch
AGU (Amyloglucosidase Units) measures glucoamylase activity against starch
GalU (Galactosidase Units) measures alpha-galactosidase activity against complex carbohydrates
FIP (International Pharmaceutical Federation units) measures lipase activity against fat
FCC (Food Chemicals Codex units) measures lactase activity against lactose
CU and BGU (Cellulase Units and Beta-Glucanase Units) measure fibre digesting activity
DP° (Degrees of Diastatic Power) measures maltase activity against starch
XU and HCU (Xylanase Units and Hemicellulase Units) measure fibre digesting activity
SU (Sumner Units) measures invertase activity against sugar
Endo PGU (Endo-Polygalacturonase Units) measures pectinase activity against fibre
PU and GDU (Papain Units and Gelatin Digesting Units) measure protease activity against protein, specific to papain and bromelain respectively
You cannot meaningfully compare activity units across different enzymes, since each one is measured against a different substrate and test method. A high DU figure for amylase and a high HUT figure for protease are not on the same scale, and neither indicates that one enzyme is stronger than the other. Activity units are only useful for comparing the same enzyme across different products.
Does this contain a proprietary blend?
No. Every enzyme is listed individually with its own disclosed activity level and amount.
Is this suitable for someone who is lactose intolerant?
The formula includes a relatively high dose of lactase specifically for lactose digestion support, and the manufacturer recommends a higher dose with lactose containing meals for this purpose. This is general manufacturer guidance, not medical advice.
Can this be taken alongside antibiotics?
The manufacturer states this product can be taken alongside antibiotics since it contains only digestive enzymes, though it recommends checking with a doctor or pharmacist if you are on prescribed medication.
Is this suitable for vegans?
Yes, per the manufacturer's stated claim.
Has this been tested for heavy metals or contaminants?
Not that CuratedFit has been able to confirm. No third party testing documentation was available at the time of this review.
Can this be opened and the powder taken without swallowing the capsule?
The manufacturer states the capsule can be pulled apart and the powder sprinkled onto cold food or a drink, to be consumed immediately afterward.
Sources:
Vitabiotics Wellzyme Digestive Enzymes Advanced product page
10/6/26
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